Clinicaltrialsgov MCP Server vs Pyscn
Two MCP servers from our science & health ranking, compared on live data - updated nightly, never sponsored.
Bottom line · 2026-09-18
Clinicaltrialsgov MCP Server records significantly more monthly package installs (9,456 vs 2,346); both are actively maintained, with commits inside the last month.
How they differ in kind
Clinicaltrialsgov MCP Server focuses on: clinicaltrialsgov-mcp-server Search ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. Pyscn focuses on: Python code analysis for AI agents: complexity, dead code, clones, coupling, and a health score. Clinicaltrialsgov MCP Server offers a remote endpoint; Pyscn is local stdio. Environment-variable extraction: Clinicaltrialsgov MCP Server yielded 2 variables; Pyscn yielded 1 variable. Implementation languages differ (TypeScript vs Go).
What each one does
Clinicaltrialsgov MCP Server
clinicaltrialsgov-mcp-server Search ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. STDIO or Streamable HTTP. Its 7 documented tools cover clinicaltrials, study.
From the project's README.
Pyscn
Python code analysis for AI agents: complexity, dead code, clones, coupling, and a health score. It runs locally over stdio via the published package.
From the project's README.
14 signals, side by side
| Signal | Clinicaltrialsgov MCP Server | Pyscn |
|---|---|---|
| Monthly installs | 9,456 | 2,346 |
| GitHub stars | 94 | 1,068 |
| Last commit | 2026-09-13 | 2026-09-17 |
| Releases · last 90 days | 10+ | 10+ |
| In the registry since | Oct 2025 | Jul 2026 |
| Registry versions | 69 | 10 |
| Documented tools | 7 | not extracted - see README |
| Env vars extracted | 2 | 1 |
| Runs | local or remote | local (stdio) |
| Endpoint auth | none (verified open) | local only |
| Maintenance | actively maintained | actively maintained |
| License | Apache-2.0 | MIT |
| Language | TypeScript | Go |
| Category rank | #4 of 71 | #3 of 71 |
What their tools cover
Extracted from each project's README - the tools each server hands your agent. A missing list means the README doesn't document one, not that no tools exist.
Clinicaltrialsgov MCP Server 7 tools documented
clinicaltrials_search_studies- Search studies with full-text and field-specific queries…clinicaltrials_get_study_record- Fetch a single study by NCT ID - full protocol record with optional…clinicaltrials_get_study_count- Fast total study count for a query, without fetching dataclinicaltrials_get_field_values- Discover valid values for API fields, with per-value study countsclinicaltrials_get_field_definitions- Resolve valid field names - keyword search, path drill-down, or…clinicaltrials_get_study_results- Fetch posted results - outcomes, adverse events, participant flow…clinicaltrials_find_eligible- Match patient demographics and conditions to eligible recruiting…
Pyscn no tool list in README
Environment variables found in the READMEs
These are extracted names, not a requiredness check. Project docs may mark them optional or require other setup.
Clinicaltrialsgov MCP Server
- MCP_TRANSPORT_TYPE
- MCP_LOG_LEVEL
Pyscn
- PYSCN_CONFIG
Which one, for what
Derived from the signals above, not hands-on testing.
Pick Clinicaltrialsgov MCP Server if…
- → you want the more widely installed option - 9,456 monthly installs vs 2,346
- → you want a hosted endpoint instead of running a local process
Pick Pyscn if…
- → you prefer a Go codebase to extend or audit
- → category standing - #3 of 71 maintained science & health servers
Who's behind them
Clinicaltrialsgov MCP Server - cyanheads: 125 MCP servers tracked, 119 maintained, 1,816 combined stars. Full record.
Pyscn - ludo-technologies: 1 MCP server tracked, 1 maintained, 1,068 combined stars.
Not sold on either?
The next-ranked science & health servers we track:
Quick answers
Is Clinicaltrialsgov MCP Server better than Pyscn?
Package installs favor Clinicaltrialsgov MCP Server: 9,456 monthly installs to 2,346. Pyscn still ranks #3 of 71 maintained science & health servers. Data as of 2026-09-18; we haven't hands-on tested either.
Can I use Clinicaltrialsgov MCP Server and Pyscn together?
Yes - MCP clients accept multiple servers in one config, so you can enable both science & health servers side by side. If their tools overlap, keep the one whose toolset fits to keep your agent's tool list lean.
What environment variables do their READMEs document?
Clinicaltrialsgov MCP Server: 2 environment variables extracted from the README setup; Pyscn: 1 environment variable extracted from the README setup. Extraction does not rule out other authentication or configuration steps; check each project's current documentation.
Keep exploring: best science & health servers · TypeScript servers · Go servers · all comparisons · every server
Methodology: package-usage signal = npm/PyPI installs (last month, platform APIs) · maintenance = commit recency + release cadence (GitHub) · tool lists and environment-variable names extracted from each project's README · endpoint auth from our own nightly probes. We haven't hand-tested these servers; everything here is data as of 2026-09-18.